10 Best 45 Long Term Travel Carry-on Backpacks [2025]
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Finding the perfect carry-on backpack for long-term travel can be a daunting task, especially with the vast array of options available on the market. With numerous brands, styles, and features to consider, it’s easy to feel overwhelmed when trying to choose the right one that meets your specific needs. Whether you are a seasoned traveler or preparing for your first adventure, the process of sifting through countless reviews and specifications can quickly become time-consuming and frustrating.
To help ease this burden, we have meticulously researched and shortlisted the best 45 long term travel carry-on backpacks, taking into account factors such as durability, comfort, organization, and versatility. Our curated list not only highlights top-performing backpacks but also serves as a valuable resource to save you time and hassle, allowing you to focus on what truly matters: your journey ahead. With our recommendations, you can embark on your travels equipped with a reliable backpack that suits your style and travel requirements.
Top 10 45 Long Term Travel Carry-on Backpacks In The Market
Best 45 Long Term Travel Carry-on Backpacks Review
Bestseller No. 1
MATEIN 45L Travel Backpack, Large Carry on Backpack for Men Women, Water...
- Expandable & Large Capacity: Dimension:20*8.6*13.4inch This extra large travel backpack with expandable feature offers you more packing capacity. Unzipping to get extra storage then can easily hold packing cubes, make-up bag, outfits, camera bag and gear, etc. It is designed for men, women, weekend traveler, or occasional vacationer. This versatile luggage backpack also meets airline carry-on requirements
- Convertible Design: The carry on backpack is designed with hideaway padded shoulder straps which can be easily stored away in zippered back panel, transforming this vacation backpack from carry-on duffel to briefcase style and provide you a more flexible carrying experience. A luggage strap on the back is designed to fit on luggage/suitcase, for easier carry on international travel or cruise. A great gifts for people who travel
- Easy to Carry: The luggage backpack is light to carry due to its adjustable shoulder straps, comfortable air-mesh ventilated back panel. 2 padded grab handles are set on the top and the side of the travel backpack, making it easily to take the bag from an overhead bin. Gift choice for Thanksgiving Day, Christmas, New Year, Valentine's Day, also available as travelers gifts
- Built for Travel: Front compartment is for little gear such as phone, earphone. The large inside pocket has internal compression elastic straps. The padded straps include a sternum strap that can be adjusted upward or downward, set to go across your chest, relieving the weight from your shoulder. 4 external compression straps keep contents from sloshing around and can get an inch or 2 more of vertical space also reduced stress on the zippers
- Heavy-duty: This large travel backpack is made of water resistant lightweight polyester with lockable zipper heads. Could be survived in different temperatures. With sturdy zippers and decent stitching, this backpack won't show any defects when on the go, ensuring you an unforgettable weekend getaway. Does your partner like to travel? It's an ideal gifts for traveler. It's also a practical Christmas and New Years gift for your parents, traveler
Bestseller No. 2
Ponhog Travel Backpack for Men, 50L Carry On Flight Approved Convertible Duffle...
- 50L LARGE CAPACITY: This travel backpack has 10 pockets, including a quick-access front pocket, a waist anti-theft pocket, a water bottle pocket, a separate shoe pocket, and a compartment for a 17.3-inch computer and tablet. The items can be stored in an orderly and safe manner, so that it is an ideal for long-distance travel for 5-7 days
- ERGONOMIC COMFORT STRAPS: The Ponhog travel carry-on backpack provides you with excellent comfort support, with an ergonomic S-shaped shoulder strap design and 2mm thick back padding to reduce the discomfort of long-term backpacking, making it easy and stress-free even in urban exploration or hiking
- TRAVEL-FRIENDLY SIZE: This carry-on backpack measures 12.2x7.87x22.04 inches. It is designed for airplane travel and can easily fit into the cabin luggage racks of most airlines. Whether you go out for the weekend, attend international events, or explore the outdoors, this large travel backpack will be your reliable partner
- 3-IN-1 VERSATILITY: The hidden shoulder strap design allows the laptop backpack to be convertible into a duffel bag, a shoulder bag and backpack in one. It is also designed with luggage straps that can be placed on the suitcase to adapt to different travel scenarios. You can choose the most convenient way to carry and enjoy a flexible travel experience
- RELIABLE MATERIAL: The men's travel backpack is made of water resistant and sturdy polyester fabric and high-density nylon lining for better tear resistance, and equipped with a metal zipper to ensure daily durable use. With a built-in USB cable and power bank pocket, this backpack is perfect for traveling. Get a travel duffle backpack to start your journey
Bestseller No. 3
TANGCORLE Travel Carry on Backpack 50L Expandable Flight Approved Backpacks 17.3...
- [36L-50L EXPANDABLE DESIGN]: The extra large carry on backpack with expandable feature gives you a spacious capacity experience. Normal state is 36L, dimensions are 19.6x8.7x12.2inch. After extended is 50L, dimensions are 19.6*11.4*12.2inch. Our suggestion is 50L backpack more suitable for tall people, recommended 5.91 feet and above. 160 pounds and above people use, more suitable for men, because the backpack is large, suitable for 5-7 days of travel
- [CONVENIENT & PRACTICAL]: Business carry on backpack has external USB port with built in charging cable. offering you charge your electronic device by your own power bank any time and anywhere. there's a luggage strap makes it fixed on luggage for easier carrying. The hidden anti theft pocket on the back side can protect you personal valuable item such as passport and wallet.
- [DURABLE & WATERPROOF]: Travel backpack is made of water-repellent fabri and anti scratch material, effectively resist rainwater splashing, protect items from getting wet. The adjustable shoulder strap and backside with breathable mesh plentiful sponge pads can helps you relieve the stress from shoulder and back.
- [MULTI-FUNCTION & FLIGHT APPROVED]: The carry on business backpack overall size meets the maximum size allowed by most airlines, fits under the seat and in the overhead bin in airplane. also the design of freely 180 degrees zipper closure making you go through the security check quickly
- [CONSTRUCTION & DEMINSION]: One separate laptop compartment size is 18.5x11.8inch fits 17.3 inch laptop. The main compartment can store 5-7 days travel gear such as clothes, shoes and daily supplies, perfect for business traveling, weekend getaway, daily commutes. ( this item is not intended for use by 12 years old and under)
Bestseller No. 4
MATEIN Extra Large 45L Travel Laptop Backpack, Airline Approved Carry on...
- Carry On Airline Approved: Avoid extra luggage fees! Designed at 21”H x 13.5”L x 8.5”W, this carry on backpack for airplanes meets most airlines carry on size requirement, and can be placed in the overhead luggage compartment, suitable for Spirit, Frontier, Easy Jet, Jet Blue, and other airlines. This carry on travel backpack features a TSA-friendly 90-180° opening design lets you breeze through security checks and keep other items tidy
- Spacious & Organized: Everything in its place! This large 45L carry on backpack stay organized with 4 main compartments, the travel backpack carry on's main compartment with double zippers has enough storage room to store like a suitcase, fits up to 3-4 days trip. The separate laptop compartment offers enhanced padding to protect your 18" laptop. The front compartment has many pockets to keep your belongings organized. The Secure hidden pocket design can protect your passport, wallet & valuables
- Versatile & Convenient: External USB port with built in charging cable conveniently charges your phone and other electronic devices (pls provide your own portable charger). The shoe compartment at the bottom fits sizes 10-12, keeping footwear separate and odors at bay with breathable venting holes, while doubling as a versatile toiletry or accessory bag. This large travel backpack ensures essentials stay neat, accessible, and travel-ready—perfect for business trips or adventures
- Practical & Comfortable: Crafted from water-repellent, high-density polyester with sturdy metal zippers, this airplane travel backpack ensures long-lasting protection. Secure your valuables with lockable metal zippers in the laptop compartment (bring your own lock). Enjoy airflow back design, multi-panel padding, and breathable, adjustable straps for stress-free carrying. Features padded handles, a luggage strap, and a side mesh pocket for water bottles or umbrellas—Travel with comfort and ease
- Perfect Travel Companion：Whether for work or travel, daily or commuting usage, short weekend trip or spontaneous adventures, our tsa backpack carry on is the perfect companion! From airline friendly carry on to lightweight hiking gear, this backpack luggage for travel has you covered. A great gifts choice for your husband, families, friends, travelers, adventurers, and anyone on the go. This item is not intended for use by 12 years old and under
Bestseller No. 5
Bestseller No. 6
45L Carry On Backpack, Weekender Travel Backpacks, 17.3 inch Laptop Back Pack...
- 【TRAVEL EXPANDABLE BACKPACK】: Bange travel backpack has the expansion design, the normal storage is 22L. When unzipping the outside, it can expand to 45L, which can meet your 5--7 business travel.
- 【LARGE CAPACITY CARRY ON BACKPACK】: BANGE mens backpack has many compartments and pockets. The main pocket can hold your travel goods,fit 5-8pcs clothes. The wet and dry separation pockets can hold your washing items and keep other items dry all the time. Front compartment can also hold magazines,Ipad and books and power bank which can charge your phone.
- 【17.3 INCH LAPTOP BACKPACK】: 45L travel backpack has a separate laptop compartment, which can hold 17inch laptop and protect laptop from moving. With high quality waterproof PVC material, your laptop can be prevent wet in the raining days.
- 【WEEKENDER BACKPACK WITH USB CHARGING】: BANGE backpack travel ensure a secure long-lasting usage everyday or weekend, it is a great companion for business trip, hiking, travel, camping and other outdoor activities. It is convenient to charge your phone from outside due to there is a USB charging port, and you only need to place a power bank in the backpack.
- 【DURABLE & MULTIPURPOSE】: The shoulder and handle joints are adopted bold line sewing to make it sturdier. The two thick handles are comfortable for long time carrying. All the zippers are durable and smooth which are sturdy explosion-proof. Different compartments with different sizes and features make you to storage items easily and neatly.
Bestseller No. 7
TOTWO Travel Backpack, Extra Large Backpack, Carry On Backpack, 52L Expandable...
- ✨【100% Lifetime Warranty】：TOTWO travel carry on backpack comes with lifetime worry-free after-sales service. If you have any issues, please don't hesitate to contact us, and we'll be more than happy to help you out. (THIS ITEM IS NOT INTENDED FOR USE BY PEOPLE 12 AND UNDER.)
- ✨【Expandable & Extra Large Capacity】: This large travel backpack can expand by 5 cm, increasing its capacity to 45L. Whether it's clothes, makeup, camera gear, or other travel essentials, this extra large travel backpack has got you covered.
- ✨【TSA Airline Approved】：The mens backpack for travel is designed to meet airline requirements and can be unfolded from 90-180° for quick security checks. A luggage strap on the back is designed to fit on the luggage's handle, for easier carry on international travel.
- ✨【USB Port Design】: This large backpack for travel has a built-in USB charger and cable, making it easy to charge your electronic devices on the go. (Note: Power bank not included.)
- ✨【Shoe Compartment】：The bottom of the luggage backpack has a shoe pocket that is large enough to accommodate men's and women's shoes in sizes 10 to 12. The shoes and other items can be stored separately to keep the contents of the backpack clean. In addition, the shoe box lining of this large backpack for men is made of waterproof material, which can also be used as a wash bag to store cleaning supplies.
Bestseller No. 8
LOVEVOOK Travel Laptop Backpack for Men, 45L Large Carry On Backpack Personal...
- 【SWISS ARMY KNIFE INSPIRED DESIGN】Our Travel Laptop Backpack is inspired by the iconic Swiss Army Knife. With dimensions of 13.5x9x20 inches, it meets airline personal item regulations and fits easily in overhead compartments and under seats. It also comes with two additional storage pouches, perfect for organizing small essentials like cables, adapters, or toiletries.
- 【EXCEPTIONAL STORAGE CAPACITY】Designed for maximum organization, this Men's Travel Backpack features three spacious compartments, each equipped with multiple functional pockets. The largest compartment opens 180 degrees, making it a breeze to pass through airport security checks. Keep your laptop, documents, and travel essentials neatly separated and easily accessible, ensuring a stress-free travel experience.
- 【COMFORT MEETS PRACTICALITY】Experience all-day comfort with the breathable, padded shoulder straps that reduce strain on your shoulders. The innovative wet-dry separation pocket keeps damp items like umbrellas or towels from affecting your other belongings. Plus, the built-in luggage strap allows you to securely attach the backpack to your suitcase handle, making it ideal for seamless travel.
- 【BUILT TO LAST】Crafted from premium tear-resistant, waterproof, and abrasion-resistant materials, this Large Carry-on Backpack is built to withstand the rigors of travel, work, hiking, or school. Its durable construction ensures long-lasting performance, no matter the environment. Whether you're navigating busy city streets or exploring rugged trails, this backpack is your reliable companion.
- 【BACKPACK FOR EVERY JOURNEY】Discover the ultimate companion for all your journeys with our Large Travel Backpack. Designed to adapt to your lifestyle, this backpack is perfect for traveling, hiking, work, school, and more. Whether you're exploring the great outdoors, commuting to the office, or heading to class, this backpack offers the perfect blend of functionality and style.
Bestseller No. 9
LOVEVOOK Carry on Backpack, 45L Large Travel Backpack for Women Men Airline...
- [45L EXPANDABLE TRAVEL BACKPACK] This versatile backpack expands from 35L to an impressive 45+L, perfect for 3-7 days of travel. It fits 3-4 sets of clothes, shoes (with a separate bag), and daily essentials, plus a 17.3-inch laptop. It is an ideal travel backpack for men and women! NOTE: This backpack is larger in size, so we recommend considering your needs before purchasing.
- [AIRLINE APPROVED] Weight: about 4 lbs. This carry on backpack the size before expansion is 20*14*7 Inces, and the size after expansion is 20*14*9 Inces, which conforms to the size (22*14*9 Inces ) regulations of most airlines for carry on baggage, such as Delta Air Lines, Alaska Airlines, Southwest Airlines, United Airlines. It’s a carry on backpack airline approved and 180-degree zipper closure to get you through security quickly
- [EXTRA 4 PACKING CUBES] Travel backpack with four packing cubes. large cube for sweaters, jackets, pants. Medium cube for shirts, shorts. Small cube for toiletries such as makeup, cleanser, etc, there's also a shoe pocket. Keeping your belongings neater and more organized. without a doubt it’s a large travel backpack. If your clothes get wet, don't worry, there is a wet pocket at the top of the large compartment, which can hold 2 T-shirts or towels
- [FOR TRAVEL] This carry on backpack is flight approved, you can travel anywhere you want, it has a side handle, it can be turned into a suitcase backpack, and there is a luggage strap on the back, which can be placed on the luggage, it's very convenient to carry. Breathable sponge mesh design on the backside and shoulder straps help for the air convection, ventilation, and heat elimination and help relieve the stress from your shoulder. It’s a nice personal item backpack
- [WORRY-FREE QUALITY]Discover our weekend backpack,engineered for durability with tear-resistant,waterproof canvas,and featuring breathable,foam-padded shoulder straps for added comfort.Reinforced straps and buckles around the pack ensure robustness for travel,camping,or any weekend adventure.LOVEVOOK PERFECT SERVICE-Our sellers attach much importance to our customer's shopping experience,Any questions,please feel free to contact us.LOVEVOOK backpack will provide you with 24-hour customer service
Bestseller No. 10
Vancropak Expandable Carry on Backpack for Airplanes, TSA Personal Item Airline...
- As Personal Item Airline Approved: Say goodbye to extra luggage fees! Sized at 18" (H) × 13" (L) × 5.5" (W) (expandable to 7.5"depth), this travel backpack for women airline approved fits the personal item limits of most major airlines such as for Spirit, Frontier, JetBlue, and Southwest. Easily slides under the seat or into overhead bins. The TSA-friendly 90–180°opening design speeds up security checks and keeps your items neat. Travel lighter, faster, and smarter—your optimal carry-on solution
- Spacious & Organized: Pack smarter, not harder! This 40L backpack travel has a large main compartment that expands from 5.5″ to 7.5″ depth, pack 3–4 days of clothing with room to spare. Three front organizer pockets keep your phone, passport and snacks within easy reach, while a concealed anti-theft back pocket secures your wallet and keys. Designed for effortless packing and quick access, this travel backpack for women turns travel chaos into seamless adventure
- 3 Extra Packing Cubes: Organizer like a pro – the travel backpack carry on flight approved has 3 Packing Cubes of different sizes for you to sort different types of clothing, Large cube for jackets, sweaters, trousers, Medium cube for shirts, shorts, blouses, Small water resistant cube are available for you to put the toiletries you need for travel, make your various travel necessities Neat and Orderly, bring you more convenience during the journey
- Practical & Comfortable: Crafted from water-resistant, anti-scratch polyester with reinforced zippers, this weekend travel backpack is built for durability. The breathable padded back panel and adjustable shoulder straps with a chest strap ensure all-day comfort. Four compression straps keep your load stable and compact. Padded grab handles on the top and side offer flexible carry options, while the rear luggage strap lets you securely attach the backpack to your suitcase for effortless travel
- Perfect Travel Companion: Whether you're jetting off for business, embarking on a weekend getaway, or exploring new horizons, the back pack for travel carry on is your great partner. Its expandable design and included packing cubes make organizing essentials effortless. Lightweight and airline-approved, it fits seamlessly in overhead compartments or under seats. A thoughtful gifts for travelers, adventurers, college, or loved ones—perfect for birthdays, holidays, or any special occasion
Bottom Line
In conclusion, finding the best 45 long term travel carry-on backpacks can significantly enhance your travel experience, making it more comfortable and organized. Our selection process involved thorough research, evaluating numerous options based on essential criteria such as durability, comfort, storage capacity, and user reviews. We meticulously curated a list of 10 products that stand out in the market, ensuring that each backpack meets the needs of long-term travelers.
By following our list, you can confidently choose a backpack that suits your travel style and requirements. Whether you’re embarking on a weekend getaway or an extended journey overseas, the right carry-on backpack will not only make packing easier but will also provide convenient access to your essentials while on the move. With our recommendations, you’re well-equipped to tackle any adventure that comes your way, knowing you have selected one of the best 45 long term travel carry-on backpacks for your needs. Happy travels!
